The Best Real Estate Markets en Mexico? Real estate investment in Mexico. mexico.vg considered each region based on affordability, cultural and natural attractions, infrastructure, economy, proximity to U.S. and a number of other factors contributing to overall appeal to tourists, retirees and, therefore, investors. The Best Mexican Real Estate Markets are: 1. Loreto, Baja California Sur 2. Merida, Yucatan 3. Guadalajara, Jalisco 4. Puerto Vallarta, Jalisco 5. Oaxaca, Oaxaca ...